Intravascular plasma oncotic pressure from plasma proteins pulls fluid into the vascular space. Interstitial hydrostatic pressure pushes fluid out of the interstitium.
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In skeletal muscle, the capillary hydrostatic pressure and the intravascular oncotic pressure are the most important factors. There is normally a small gradient favoring filtration out of the vascular space into the interstitium; the excess fluid is removed via the lymphatic system. An increase in capillary hydrostatic pressure for example, increased plasma volume due to renal sodium retention. An increase in capillary permeability for example, burns, angioedema.
An increase in interstitial oncotic pressure for example, myxedema.
A decrease in plasma oncotic pressure for example, hypoalbuminemia. Although it is possible to construct a pathophysiologic framework Figure for the differential diagnosis of edema, it is more useful clinically to use the distribution of the edema as the pivotal point:. Pathophysiology of edema. Adapted with permission from Cho S et al.
Peripheral edema. Am J Med.
Bilateral leg edema. Due to a systemic cause with or without presacral edema, ascites, pleural effusion, pulmonary edema, periorbital edema.http://diana116.ru/includes/tallapoosa/4023-seks-znakomstva.php
The most common systemic causes of edema are cardiac, hepatic, and renal diseases. Forgot Password? What is MyAccess? Otherwise it is hidden from view. Forgot Username? About MyAccess If your institution subscribes to this resource, and you don't have a MyAccess Profile, please contact your library's reference desk for information on how to gain access to this resource from off-campus. Sign in via OpenAthens. Sign in via Shibboleth.
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